COMBINATION OF ORIDONIN AND TRAIL INDUCES APOPTOSIS IN UVEAL MELANOMA CELLS BY UPREGULATING DR5



Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

Summary: Few therapies target the loss of tumor suppressor genes in cancer.We examine CRISPR-SpCas9 and RNA-interference loss-of-function screens to identify NHL Set new therapeutic targets associated with genomic loss of tumor suppressor genes.The endosomal sorting complexes required for transport (ESCRT) ATPases VPS4A and VPS4B score as strong sy

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Instrument constituencies and epistemic community theory

This contribution fleshes out the insights that the epistemic community (EC) approach can make to studying the public policy process and to how policy instruments are formulated and implemented.This contribution Playsuit places the EC concept in the context of how policy instruments evolve and are supported by a separate network type, the instrumen

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